PDB 4jt8

PDB Information

PDB4JT8
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3.
Disch, J.S., Evindar, G., Chiu, C.H., Blum, C.A., Dai, H., Jin, L., Schuman, E., Lind, K.E., Belyanskaya, S.L., Deng, J., Coppo, F., Aquilani, L., Graybill, T.L., Cuozzo, J.W., Lavu, S., Mao, C., Vlasuk, G.P., Perni, R.B.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-03-22
Resolution2.260
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4jt8A01 09 Aug, 2013 3.40.50.1220 Assigned
4jt8A02 09 Aug, 2013 3.30.1600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NTG7 SIR3_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-3, mitochondrial
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