PDB 4jt8
PDB Information
PDB | 4JT8 |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3.
J.Med.Chem.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2013-03-22 |
Resolution | 2.260 |
CATH Insert Date | 07 Jul, 2013 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 08 Jul, 2013 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4jt8A01 | 09 Aug, 2013 | 3.40.50.1220 | Assigned |
4jt8A02 | 09 Aug, 2013 | 3.30.1600.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
Q9NTG7 | SIR3_HUMAN | Homo sapiens | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |