PDB 4jsq

PDB Links
Overview

PDB Information

PDB	4JSQ
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Dimerized linear mimics of a natural cyclopeptide (TMC-95A) are potent noncovalent inhibitors of the eukaryotic 20S proteasome Desvergne, A., Genin, E., Marechal, X., Gallastegui, N., Dufau, L., Richy, N., Groll, M., Vidal, J., Reboud-Ravaux, M. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-03-22
Resolution	2.800
CATH Insert Date	07 Jul, 2013

PDB Images (59)

4jsq

PDB 4jsq

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PDB Chain 4jsqa

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CATH Domain 4jsqa00

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PDB Prints

PDB Chains (30)

Chain ID	Date inserted into CATH	CATH Status
a	08 Jul, 2013	Chopped
A	08 Jul, 2013	Chopped
b	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped
c	08 Jul, 2013	Rejected
C	08 Jul, 2013	Chopped
d	08 Jul, 2013	Rejected
D	08 Jul, 2013	Chopped
E	08 Jul, 2013	Chopped
F	08 Jul, 2013	Chopped
G	08 Jul, 2013	Chopped
H	08 Jul, 2013	Chopped
I	08 Jul, 2013	Chopped
J	08 Jul, 2013	Chopped
K	08 Jul, 2013	Chopped
L	08 Jul, 2013	Chopped
M	08 Jul, 2013	Chopped
N	08 Jul, 2013	Chopped
O	08 Jul, 2013	Chopped
P	08 Jul, 2013	Chopped
Q	08 Jul, 2013	Chopped
R	08 Jul, 2013	Chopped
S	08 Jul, 2013	Chopped
T	08 Jul, 2013	Chopped
U	08 Jul, 2013	Chopped
V	08 Jul, 2013	Chopped
W	08 Jul, 2013	Chopped
X	08 Jul, 2013	Chopped
Y	08 Jul, 2013	Chopped
Z	08 Jul, 2013	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4jsqa00	09 Aug, 2013	3.60.20.10	Assigned
4jsqA00	09 Aug, 2013	3.60.20.10	Assigned
4jsqb00	09 Aug, 2013	3.60.20.10	Assigned
4jsqB00	09 Aug, 2013	3.60.20.10	Assigned
4jsqC00	09 Aug, 2013	3.60.20.10	Assigned
4jsqD00	09 Aug, 2013	3.60.20.10	Assigned
4jsqE00	09 Aug, 2013	3.60.20.10	Assigned
4jsqF00	09 Aug, 2013	3.60.20.10	Assigned
4jsqG00	09 Aug, 2013	3.60.20.10	Assigned
4jsqH00	09 Aug, 2013	3.60.20.10	Assigned
4jsqI00	09 Aug, 2013	3.60.20.10	Assigned
4jsqJ00	09 Aug, 2013	3.60.20.10	Assigned
4jsqK00	09 Aug, 2013	3.60.20.10	Assigned
4jsqL00	09 Aug, 2013	3.60.20.10	Assigned
4jsqM00	09 Aug, 2013	3.60.20.10	Assigned
4jsqN00	09 Aug, 2013	3.60.20.10	Assigned
4jsqO00	09 Aug, 2013	3.60.20.10	Assigned
4jsqP00	09 Aug, 2013	3.60.20.10	Assigned
4jsqQ00	09 Aug, 2013	3.60.20.10	Assigned
4jsqR00	09 Aug, 2013	3.60.20.10	Assigned
4jsqS00	09 Aug, 2013	3.60.20.10	Assigned
4jsqT00	09 Aug, 2013	3.60.20.10	Assigned
4jsqU00	09 Aug, 2013	3.60.20.10	Assigned
4jsqV00	09 Aug, 2013	3.60.20.10	Assigned
4jsqW00	09 Aug, 2013	3.60.20.10	Assigned
4jsqX00	09 Aug, 2013	3.60.20.10	Assigned
4jsqY00	09 Aug, 2013	3.60.20.10	Assigned
4jsqZ00	09 Aug, 2013	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7