PDB 4jnk

PDB Information

PDB4JNK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase.
Dragovich, P.S., Fauber, B.P., Corson, L.B., Ding, C.Z., Eigenbrot, C., Ge, H., Giannetti, A.M., Hunsaker, T., Labadie, S., Liu, Y., Malek, S., Pan, B., Peterson, D., Pitts, K., Purkey, H.E., Sideris, S., Ultsch, M., Vanderporten, E., Wei, B., Xu, Q., Yen, I., Yue, Q., Zhang, H., Zhang, X.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-03-15
Resolution1.900
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4jnkA01 09 Aug, 2013 3.40.50.720 Assigned
4jnkA02 09 Aug, 2013 3.90.110.10 Assigned
4jnkB01 09 Aug, 2013 3.40.50.720 Assigned
4jnkB02 09 Aug, 2013 3.90.110.10 Assigned
4jnkC01 09 Aug, 2013 3.40.50.720 Assigned
4jnkC02 09 Aug, 2013 3.90.110.10 Assigned
4jnkD01 09 Aug, 2013 3.40.50.720 Assigned
4jnkD02 09 Aug, 2013 3.90.110.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
P00338 LDHA_HUMAN Homo sapiens L-lactate dehydrogenase A chain
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