PDB Information

PDB4JIA
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors.
Siu, M., Pastor, R., Liu, W., Barrett, K., Berry, M., Blair, W.S., Chang, C., Chen, J.Z., Eigenbrot, C., Ghilardi, N., Gibbons, P., He, H., Hurley, C.A., Kenny, J.R., Cyrus Khojasteh, S., Le, H., Lee, L., Lyssikatos, J.P., Magnuson, S., Pulk, R., Tsui, V., Ultsch, M., Xiao, Y., Zhu, B.Y., Sampath, D.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-03-05
Resolution1.850
CATH Insert Date01 Sep, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4jiaA01 03 Sep, 2013 3.30.200.20 Assigned
4jiaA02 03 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
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