PDB 4j70

PDB Links
Overview

PDB Information

PDB	4J70
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action. Kawamura, S., Unno, Y., List, A., Mizuno, A., Tanaka, M., Sasaki, T., Arisawa, M., Asai, A., Groll, M., Shuto, S. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-02-12
Resolution	2.800
CATH Insert Date	07 Jul, 2013

PDB Images (57)

4j70

PDB 4j70

4j70a

PDB Chain 4j70a

4j70A

PDB Chain 4j70A

4j70b

PDB Chain 4j70b

4j70B

PDB Chain 4j70B

4j70C

PDB Chain 4j70C

4j70D

PDB Chain 4j70D

4j70E

PDB Chain 4j70E

4j70F

PDB Chain 4j70F

4j70G

PDB Chain 4j70G

4j70H

PDB Chain 4j70H

4j70I

PDB Chain 4j70I

4j70J

PDB Chain 4j70J

4j70K

PDB Chain 4j70K

4j70L

PDB Chain 4j70L

4j70M

PDB Chain 4j70M

4j70N

PDB Chain 4j70N

4j70O

PDB Chain 4j70O

4j70P

PDB Chain 4j70P

4j70Q

PDB Chain 4j70Q

4j70R

PDB Chain 4j70R

4j70S

PDB Chain 4j70S

4j70T

PDB Chain 4j70T

4j70U

PDB Chain 4j70U

4j70V

PDB Chain 4j70V

4j70W

PDB Chain 4j70W

4j70X

PDB Chain 4j70X

4j70Y

PDB Chain 4j70Y

4j70Z

PDB Chain 4j70Z

4j70a00

CATH Domain 4j70a00

4j70A00

CATH Domain 4j70A00

4j70b00

CATH Domain 4j70b00

4j70B00

CATH Domain 4j70B00

4j70C00

CATH Domain 4j70C00

4j70D00

CATH Domain 4j70D00

4j70E00

CATH Domain 4j70E00

4j70F00

CATH Domain 4j70F00

4j70G00

CATH Domain 4j70G00

4j70H00

CATH Domain 4j70H00

4j70I00

CATH Domain 4j70I00

4j70J00

CATH Domain 4j70J00

4j70K00

CATH Domain 4j70K00

4j70L00

CATH Domain 4j70L00

4j70M00

CATH Domain 4j70M00

4j70N00

CATH Domain 4j70N00

4j70O00

CATH Domain 4j70O00

4j70P00

CATH Domain 4j70P00

4j70Q00

CATH Domain 4j70Q00

4j70R00

CATH Domain 4j70R00

4j70S00

CATH Domain 4j70S00

4j70T00

CATH Domain 4j70T00

4j70U00

CATH Domain 4j70U00

4j70V00

CATH Domain 4j70V00

4j70W00

CATH Domain 4j70W00

4j70X00

CATH Domain 4j70X00

4j70Y00

CATH Domain 4j70Y00

4j70Z00

CATH Domain 4j70Z00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	08 Jul, 2013	Chopped
A	08 Jul, 2013	Chopped
b	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped
C	08 Jul, 2013	Chopped
D	08 Jul, 2013	Chopped
E	08 Jul, 2013	Chopped
F	08 Jul, 2013	Chopped
G	08 Jul, 2013	Chopped
H	08 Jul, 2013	Chopped
I	08 Jul, 2013	Chopped
J	08 Jul, 2013	Chopped
K	08 Jul, 2013	Chopped
L	08 Jul, 2013	Chopped
M	08 Jul, 2013	Chopped
N	08 Jul, 2013	Chopped
O	08 Jul, 2013	Chopped
P	08 Jul, 2013	Chopped
Q	08 Jul, 2013	Chopped
R	08 Jul, 2013	Chopped
S	08 Jul, 2013	Chopped
T	08 Jul, 2013	Chopped
U	08 Jul, 2013	Chopped
V	08 Jul, 2013	Chopped
W	08 Jul, 2013	Chopped
X	08 Jul, 2013	Chopped
Y	08 Jul, 2013	Chopped
Z	08 Jul, 2013	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4j70a00	09 Aug, 2013	3.60.20.10	Assigned
4j70A00	09 Aug, 2013	3.60.20.10	Assigned
4j70b00	09 Aug, 2013	3.60.20.10	Assigned
4j70B00	09 Aug, 2013	3.60.20.10	Assigned
4j70C00	09 Aug, 2013	3.60.20.10	Assigned
4j70D00	09 Aug, 2013	3.60.20.10	Assigned
4j70E00	09 Aug, 2013	3.60.20.10	Assigned
4j70F00	09 Aug, 2013	3.60.20.10	Assigned
4j70G00	09 Aug, 2013	3.60.20.10	Assigned
4j70H00	09 Aug, 2013	3.60.20.10	Assigned
4j70I00	09 Aug, 2013	3.60.20.10	Assigned
4j70J00	09 Aug, 2013	3.60.20.10	Assigned
4j70K00	09 Aug, 2013	3.60.20.10	Assigned
4j70L00	09 Aug, 2013	3.60.20.10	Assigned
4j70M00	09 Aug, 2013	3.60.20.10	Assigned
4j70N00	09 Aug, 2013	3.60.20.10	Assigned
4j70O00	09 Aug, 2013	3.60.20.10	Assigned
4j70P00	09 Aug, 2013	3.60.20.10	Assigned
4j70Q00	09 Aug, 2013	3.60.20.10	Assigned
4j70R00	09 Aug, 2013	3.60.20.10	Assigned
4j70S00	09 Aug, 2013	3.60.20.10	Assigned
4j70T00	09 Aug, 2013	3.60.20.10	Assigned
4j70U00	09 Aug, 2013	3.60.20.10	Assigned
4j70V00	09 Aug, 2013	3.60.20.10	Assigned
4j70W00	09 Aug, 2013	3.60.20.10	Assigned
4j70X00	09 Aug, 2013	3.60.20.10	Assigned
4j70Y00	09 Aug, 2013	3.60.20.10	Assigned
4j70Z00	09 Aug, 2013	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5