PDB 4j1f

PDB Information

PDB4J1F
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease
Hilpert, H., Guba, W., Woltering, T.J., Wostl, W., Pinard, E., Mauser, H., Mayweg, A.V., Rogers-Evans, M., Humm, R., Krummenacher, D., Muser, T., Schnider, C., Jacobsen, H., Ozmen, L., Bergadano, A., Banner, D.W., Hochstrasser, R., Kuglstatter, A., David-Pierson, P., Fischer, H., Polara, A., Narquizian, R.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-02-01
Resolution2.250
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4j1fA01 09 Aug, 2013 2.40.70.10 Assigned
4j1fA02 09 Aug, 2013 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1