PDB 4inu

PDB Links
Overview

PDB Information

PDB	4INU
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites. Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-01-06
Resolution	3.100
CATH Insert Date	03 Feb, 2013

PDB Images (57)

4inu

PDB 4inu

4inua

PDB Chain 4inua

4inuA

PDB Chain 4inuA

4inub

PDB Chain 4inub

4inuB

PDB Chain 4inuB

4inuC

PDB Chain 4inuC

4inuD

PDB Chain 4inuD

4inuE

PDB Chain 4inuE

4inuF

PDB Chain 4inuF

4inuG

PDB Chain 4inuG

4inuH

PDB Chain 4inuH

4inuI

PDB Chain 4inuI

4inuJ

PDB Chain 4inuJ

4inuK

PDB Chain 4inuK

4inuL

PDB Chain 4inuL

4inuM

PDB Chain 4inuM

4inuN

PDB Chain 4inuN

4inuO

PDB Chain 4inuO

4inuP

PDB Chain 4inuP

4inuQ

PDB Chain 4inuQ

4inuR

PDB Chain 4inuR

4inuS

PDB Chain 4inuS

4inuT

PDB Chain 4inuT

4inuU

PDB Chain 4inuU

4inuV

PDB Chain 4inuV

4inuW

PDB Chain 4inuW

4inuX

PDB Chain 4inuX

4inuY

PDB Chain 4inuY

4inuZ

PDB Chain 4inuZ

4inua00

CATH Domain 4inua00

4inuA00

CATH Domain 4inuA00

4inub00

CATH Domain 4inub00

4inuB00

CATH Domain 4inuB00

4inuC00

CATH Domain 4inuC00

4inuD00

CATH Domain 4inuD00

4inuE00

CATH Domain 4inuE00

4inuF00

CATH Domain 4inuF00

4inuG00

CATH Domain 4inuG00

4inuH00

CATH Domain 4inuH00

4inuI00

CATH Domain 4inuI00

4inuJ00

CATH Domain 4inuJ00

4inuK00

CATH Domain 4inuK00

4inuL00

CATH Domain 4inuL00

4inuM00

CATH Domain 4inuM00

4inuN00

CATH Domain 4inuN00

4inuO00

CATH Domain 4inuO00

4inuP00

CATH Domain 4inuP00

4inuQ00

CATH Domain 4inuQ00

4inuR00

CATH Domain 4inuR00

4inuS00

CATH Domain 4inuS00

4inuT00

CATH Domain 4inuT00

4inuU00

CATH Domain 4inuU00

4inuV00

CATH Domain 4inuV00

4inuW00

CATH Domain 4inuW00

4inuX00

CATH Domain 4inuX00

4inuY00

CATH Domain 4inuY00

4inuZ00

CATH Domain 4inuZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	04 Feb, 2013	Chopped
A	04 Feb, 2013	Chopped
b	04 Feb, 2013	Chopped
B	04 Feb, 2013	Chopped
C	04 Feb, 2013	Chopped
D	04 Feb, 2013	Chopped
E	04 Feb, 2013	Chopped
F	04 Feb, 2013	Chopped
G	04 Feb, 2013	Chopped
H	04 Feb, 2013	Chopped
I	04 Feb, 2013	Chopped
J	04 Feb, 2013	Chopped
K	04 Feb, 2013	Chopped
L	04 Feb, 2013	Chopped
M	04 Feb, 2013	Chopped
N	04 Feb, 2013	Chopped
O	04 Feb, 2013	Chopped
P	04 Feb, 2013	Chopped
Q	04 Feb, 2013	Chopped
R	04 Feb, 2013	Chopped
S	04 Feb, 2013	Chopped
T	04 Feb, 2013	Chopped
U	04 Feb, 2013	Chopped
V	04 Feb, 2013	Chopped
W	04 Feb, 2013	Chopped
X	04 Feb, 2013	Chopped
Y	04 Feb, 2013	Chopped
Z	04 Feb, 2013	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4inua00	11 Feb, 2013	3.60.20.10	Assigned
4inuA00	11 Feb, 2013	3.60.20.10	Assigned
4inub00	11 Feb, 2013	3.60.20.10	Assigned
4inuB00	11 Feb, 2013	3.60.20.10	Assigned
4inuC00	11 Feb, 2013	3.60.20.10	Assigned
4inuD00	11 Feb, 2013	3.60.20.10	Assigned
4inuE00	11 Feb, 2013	3.60.20.10	Assigned
4inuF00	11 Feb, 2013	3.60.20.10	Assigned
4inuG00	11 Feb, 2013	3.60.20.10	Assigned
4inuH00	11 Feb, 2013	3.60.20.10	Assigned
4inuI00	11 Feb, 2013	3.60.20.10	Assigned
4inuJ00	11 Feb, 2013	3.60.20.10	Assigned
4inuK00	11 Feb, 2013	3.60.20.10	Assigned
4inuL00	11 Feb, 2013	3.60.20.10	Assigned
4inuM00	11 Feb, 2013	3.60.20.10	Assigned
4inuN00	11 Feb, 2013	3.60.20.10	Assigned
4inuO00	11 Feb, 2013	3.60.20.10	Assigned
4inuP00	11 Feb, 2013	3.60.20.10	Assigned
4inuQ00	11 Feb, 2013	3.60.20.10	Assigned
4inuR00	11 Feb, 2013	3.60.20.10	Assigned
4inuS00	11 Feb, 2013	3.60.20.10	Assigned
4inuT00	11 Feb, 2013	3.60.20.10	Assigned
4inuU00	11 Feb, 2013	3.60.20.10	Assigned
4inuV00	11 Feb, 2013	3.60.20.10	Assigned
4inuW00	11 Feb, 2013	3.60.20.10	Assigned
4inuX00	11 Feb, 2013	3.60.20.10	Assigned
4inuY00	11 Feb, 2013	3.60.20.10	Assigned
4inuZ00	11 Feb, 2013	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1