PDB Information

PDB4IJQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Acyclic nucleoside phosphonates containing a second phosphonate group are potent inhibitors of 6-oxopurine phosphoribosyltransferases and have antimalarial activity
Keough, D.T., Spacek, P., Hockova, D., Tichy, T., Vrbkova, S., Slavetinska, L., Janeba, Z., Naesens, L., Edstein, M.D., Chavchich, M., Wang, T.H., Jersey, J., Guddat, L.W.
J.Med.Chem.
HeaderTransferase
Released2012-12-22
Resolution2.000
CATH Insert Date07 Jul, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ijqA00 09 Aug, 2013 3.40.50.2020 Assigned
4ijqB00 09 Aug, 2013 3.40.50.2020 Assigned
4ijqC00 09 Aug, 2013 3.40.50.2020 Assigned
4ijqD00 09 Aug, 2013 3.40.50.2020 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
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