PDB 4igs

PDB Information

PDB4IGS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of a novel polyfluorinated compound as a lead to inhibit the human enzymes aldose reductase and AKR1B10: structure determination of both ternary complexes and implications for drug design.
Cousido-Siah, A., Ruiz, F.X., Mitschler, A., Porte, S., de Lera, A.R., Martin, M.J., Manzanaro, S., de la Fuente, J.A., Terwesten, F., Betz, M., Klebe, G., Farres, J., Pares, X., Podjarny, A.
Acta Crystallogr.,Sect.D
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-12-18
Resolution0.850
CATH Insert Date23 Mar, 2014

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2014 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4igsA00 17 Apr, 2014 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1
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