PDB Information

PDB4IEA
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers.
Molzan, M., Kasper, S., Roglin, L., Skwarczynska, M., Sassa, T., Inoue, T., Breitenbuecher, F., Ohkanda, J., Kato, N., Schuler, M., Ottmann, C.
Acs Chem.Biol.
HeaderPeptide Binding Protein
Released2012-12-13
Resolution1.700
CATH Insert Date06 Oct, 2013

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
P 07 Oct, 2013 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4ieaA00 10 Oct, 2013 1.20.190.20 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P04049 RAF1_HUMAN Homo sapiens RAF proto-oncogene serine/threonine-protein kinase
P31947 1433S_HUMAN Homo sapiens 14-3-3 protein sigma