PDB Information

PDB4I7B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design of covalent siah inhibitors.
Stebbins, J.L., Santelli, E., Feng, Y., De, S.K., Purves, A., Motamedchaboki, K., Wu, B., Ronai, Z.A., Liddington, R.C., Pellecchia, M.
Chem.Biol.
HeaderLigase/Ligase Inhibitor
Released2012-11-30
Resolution3.000
CATH Insert Date01 Sep, 2013

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped
B 02 Sep, 2013 Rejected
C 02 Sep, 2013 Chopped
D 02 Sep, 2013 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4i7bA01 04 Sep, 2013 3.30.40.10 Assigned
4i7bA02 04 Sep, 2013 2.60.210.10 Assigned
4i7bC01 04 Sep, 2013 3.30.40.10 Assigned
4i7bC02 04 Sep, 2013 2.60.210.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1
Q8IUQ4 SIAH1_HUMAN Homo sapiens E3 ubiquitin-protein ligase SIAH1