PDB Information

PDB4I0S
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors.
Padilla, F., Bhagirath, N., Chen, S., Chiao, E., Goldstein, D.M., Hermann, J.C., Hsu, J., Kennedy-Smith, J.J., Kuglstatter, A., Liao, C., Liu, W., Lowrie, L.E., Luk, K.C., Lynch, S.M., Menke, J., Niu, L., Owens, T.D., O-Yang, C., Railkar, A., Schoenfeld, R.C., Slade, M., Steiner, S., Tan, Y.C., Villasenor, A.G., Wang, C., Wanner, J., Xie, W., Xu, D., Zhang, X., Zhou, M., Lucas, M.C.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-11-19
Resolution1.980
CATH Insert Date03 Nov, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 04 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4i0sA01 08 Nov, 2013 3.30.200.20 Assigned
4i0sA02 08 Nov, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
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