PDB 4i0e

PDB Information

PDB4I0E
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.
Xu, Y.Z., Yuan, S., Bowers, S., Hom, R.K., Chan, W., Sham, H.L., Zhu, Y.L., Beroza, P., Pan, H., Brecht, E., Yao, N., Lougheed, J., Yan, J., Tam, D., Ren, Z., Ruslim, L., Bova, M.P., Artis, D.R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-11-16
Resolution1.700
CATH Insert Date28 Mar, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4i0eA01 10 Apr, 2013 2.40.70.10 Assigned
4i0eA02 10 Apr, 2013 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1