PDB 4i0d

PDB Information

PDB4I0D
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitors.
Xu, Y.Z., Yuan, S., Bowers, S., Hom, R.K., Chan, W., Sham, H.L., Zhu, Y.L., Beroza, P., Pan, H., Brecht, E., Yao, N., Lougheed, J., Yan, J., Tam, D., Ren, Z., Ruslim, L., Bova, M.P., Artis, D.R.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-11-16
Resolution1.910
CATH Insert Date13 Oct, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 14 Oct, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4i0dA01 17 Oct, 2013 2.40.70.10 Assigned
4i0dA02 17 Oct, 2013 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1