PDB 4hy0

PDB Information

PDB4HY0
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2-a]pyrazine Scaffold as a Novel Proline Mimetic.
Hashimoto, K., Saito, B., Miyamoto, N., Oguro, Y., Tomita, D., Shiokawa, Z., Asano, M., Kakei, H., Taya, N., Kawasaki, M., Sumi, H., Yabuki, M., Iwai, K., Yoshida, S., Yoshimatsu, M., Aoyama, K., Kosugi, Y., Kojima, T., Morishita, N., Dougan, D.R., Snell, G.P., Imamura, S., Ishikawa, T.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2012-11-12
Resolution2.840
CATH Insert Date03 Feb, 2013

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 04 Feb, 2013 Chopped
B 04 Feb, 2013 Chopped
C 04 Feb, 2013 Chopped
D 04 Feb, 2013 Chopped
E 04 Feb, 2013 Chopped
F 04 Feb, 2013 Chopped
G 04 Feb, 2013 Chopped
H 04 Feb, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4hy0A00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0B00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0C00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0D00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0E00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0F00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0G00 11 Feb, 2013 1.10.1170.10 Assigned
4hy0H00 11 Feb, 2013 1.10.1170.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP
P98170 XIAP_HUMAN Homo sapiens E3 ubiquitin-protein ligase XIAP