PDB Information

PDB4HWT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of bacteria-selective threonyl-tRNA synthetase substrate inhibitors by structure-based design.
Teng, M., Hilgers, M.T., Cunningham, M.L., Borchardt, A., Locke, J.B., Abraham, S., Haley, G., Kwan, B.P., Hall, C., Hough, G.W., Shaw, K.J., Finn, J.
J.Med.Chem.
HeaderLigase/Ligase Inhibitor
Released2012-11-08
Resolution2.300
CATH Insert Date22 Sep, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Sep, 2013 Chopped
B 23 Sep, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4hwtA01 25 Sep, 2013 3.30.930.10 Assigned
4hwtA02 25 Sep, 2013 3.40.50.800 Assigned
4hwtB01 03 Oct, 2013 3.30.930.10 Assigned
4hwtB02 03 Oct, 2013 3.40.50.800 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26639 SYTC_HUMAN Homo sapiens Threonine--tRNA ligase, cytoplasmic
P26639 SYTC_HUMAN Homo sapiens Threonine--tRNA ligase, cytoplasmic
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