PDB Information

PDB4HVG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models.
Soth, M., Hermann, J.C., Yee, C., Alam, M., Barnett, J.W., Berry, P., Browner, M.F., Frank, K., Frauchiger, S., Harris, S., He, Y., Hekmat-Nejad, M., Hendricks, T., Henningsen, R., Hilgenkamp, R., Ho, H., Hoffman, A., Hsu, P.Y., Hu, D.Q., Itano, A., Jaime-Figueroa, S., Jahangir, A., Jin, S., Kuglstatter, A., Kutach, A.K., Liao, C., Lynch, S., Menke, J., Niu, L., Patel, V., Railkar, A., Roy, D., Shao, A., Shaw, D., Steiner, S., Sun, Y., Tan, S.L., Wang, S., Vu, M.D.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-11-06
Resolution2.750
CATH Insert Date27 Jan, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Jan, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hvgA01 25 Apr, 2013 3.30.200.20 Assigned
4hvgA02 25 Apr, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P52333 JAK3_HUMAN Homo sapiens Tyrosine-protein kinase JAK3
CATH-Gene3D is a Global Biodata Core Resource Learn more...