PDB Information

PDB4HVB
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design.
Cheng, H., Li, C., Bailey, S., Baxi, S.M., Goulet, L., Guo, L., Hoffman, J., Jiang, Y., Johnson, T.O., Johnson, T.W., Knighton, D.R., Li, J., Liu, K.K., Liu, Z., Marx, M.A., Walls, M., Wells, P.A., Yin, M.J., Zhu, J., Zientek, M.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2012-11-05
Resolution2.350
CATH Insert Date24 Nov, 2013

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 25 Nov, 2013 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4hvbA01 27 Nov, 2013 3.10.20.90 Assigned
4hvbA02 27 Nov, 2013 2.60.40.150 Assigned
4hvbA03 27 Nov, 2013 1.25.40.70 Assigned
4hvbA04 27 Nov, 2013 3.30.1010.10 Assigned
4hvbA05 27 Nov, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
CATH-Gene3D is a Global Biodata Core Resource Learn more...