PDB Information

PDB4HMN
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Morpholylureas are a new class of potent and selective inhibitors of the type 5 17-beta-hydroxysteroid dehydrogenase (AKR1C3).
Flanagan, J.U., Atwell, G.J., Heinrich, D.M., Brooke, D.G., Silva, S., Rigoreau, L.J., Trivier, E., Turnbull, A.P., Raynham, T., Jamieson, S.M., Denny, W.A.
Bioorg.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-10-18
Resolution2.400
CATH Insert Date17 Nov, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 18 Nov, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4hmnA00 20 Nov, 2013 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3
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