PDB 4hle

PDB Links
Overview

PDB Information

PDB	4HLE
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Cis-Amide isosteric replacement in thienobenzoxepin inhibitors of PI3-kinase. Staben, S.T., Blaquiere, N., Tsui, V., Kolesnikov, A., Do, S., Bradley, E.K., Dotson, J., Goldsmith, R., Heffron, T.P., Lesnick, J., Lewis, C., Murray, J., Nonomiya, J., Olivero, A.G., Pang, J., Rouge, L., Salphati, L., Wei, B., Wiesmann, C., Wu, P. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-10-16
Resolution	2.780
CATH Insert Date	20 Jan, 2013

PDB Images (7)

Image of CATH 4hle

4hle

PDB 4hle

Image of CATH 4hleA

4hleA

PDB Chain 4hleA

Image of CATH 4hleA01

4hleA01

CATH Domain 4hleA01

Image of CATH 4hleA02

4hleA02

CATH Domain 4hleA02

Image of CATH 4hleA03

4hleA03

CATH Domain 4hleA03

Image of CATH 4hleA04

4hleA04

CATH Domain 4hleA04

Image of CATH 4hleA05

4hleA05

CATH Domain 4hleA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	21 Jan, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4hleA01	10 Oct, 2013	3.10.20.90	Assigned
4hleA02	10 Oct, 2013	2.60.40.150	Assigned
4hleA03	10 Oct, 2013	1.25.40.70	Assigned
4hleA04	10 Oct, 2013	3.30.1010.10	Assigned
4hleA05	10 Oct, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform