PDB Information

PDB4HKP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Novel cytidine-based orotidine-5'-monophosphate decarboxylase inhibitors with an unusual twist.
Purohit, M.K., Poduch, E., Wei, L.W., Crandall, I.E., To, T., Kain, K.C., Pai, E.F., Kotra, L.P.
J.Med.Chem.
HeaderLyase/Lyase Inhibitor
Released2012-10-15
Resolution1.750
CATH Insert Date18 Nov, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Nov, 2012 Chopped
B 19 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hkpA00 03 Jan, 2013 3.20.20.70 Assigned
4hkpB00 03 Jan, 2013 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11172 UMPS_HUMAN Homo sapiens Uridine 5'-monophosphate synthase
P11172 UMPS_HUMAN Homo sapiens Uridine 5'-monophosphate synthase