PDB Information

PDB4HIQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.
Penchala, S.C., Connelly, S., Wang, Y., Park, M.S., Zhao, L., Baranczak, A., Rappley, I., Vogel, H., Liedtke, M., Witteles, R.M., Powers, E.T., Reixach, N., Chan, W.K., Wilson, I.A., Kelly, J.W., Graef, I.A., Alhamadsheh, M.M.
Proc.Natl.Acad.Sci.USA
HeaderHormone Binding Protein/Inhibitor
Released2012-10-11
Resolution1.180
CATH Insert Date07 Jul, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hiqA00 09 Aug, 2013 2.60.40.180 Assigned
4hiqB00 09 Aug, 2013 2.60.40.180 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P02766 TTHY_HUMAN Homo sapiens Transthyretin
P02766 TTHY_HUMAN Homo sapiens Transthyretin
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