PDB 4hfz
PDB Information
| PDB | 4HFZ |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant.
Acta Crystallogr.,Sect.D
|
| Header | Ligase |
| Released | 2012-10-05 |
| Resolution | 2.690 |
| CATH Insert Date | 18 Aug, 2013 |
PDB Prints
PDB Chains (4)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 19 Aug, 2013 | Chopped |
| B | 19 Aug, 2013 | Rejected |
| C | 19 Aug, 2013 | Chopped |
| D | 19 Aug, 2013 | Rejected |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4hfzA00 | 23 Aug, 2013 | 1.10.245.10 | Assigned |
| 4hfzC00 | 27 Aug, 2013 | 1.10.245.10 | Assigned |
UniProtKB Entries (4)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q00987 | MDM2_HUMAN | Homo sapiens | E3 ubiquitin-protein ligase Mdm2 |
| P04637 | P53_HUMAN | Homo sapiens | Cellular tumor antigen p53 |
| Q00987 | MDM2_HUMAN | Homo sapiens | E3 ubiquitin-protein ligase Mdm2 |
| P04637 | P53_HUMAN | Homo sapiens | Cellular tumor antigen p53 |