PDB Information

PDB4HCU
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Covalent inhibitors of interleukin-2 inducible T cell kinase (itk) with nanomolar potency in a whole-blood assay.
Zapf, C.W., Gerstenberger, B.S., Xing, L., Limburg, D.C., Anderson, D.R., Caspers, N., Han, S., Aulabaugh, A., Kurumbail, R., Shakya, S., Li, X., Spaulding, V., Czerwinski, R.M., Seth, N., Medley, Q.G.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-10-01
Resolution1.430
CATH Insert Date18 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 19 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4hcuA01 02 Jan, 2013 3.30.200.20 Assigned
4hcuA02 02 Jan, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
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