PDB 4hbx

PDB Information

PDB4HBX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit.
Fish, P.V., Filippakopoulos, P., Bish, G., Brennan, P.E., Bunnage, M.E., Cook, A.S., Federov, O., Gerstenberger, B.S., Jones, H., Knapp, S., Marsden, B., Nocka, K., Owen, D.R., Philpott, M., Picaud, S., Primiano, M.J., Ralph, M.J., Sciammetta, N., Trzupek, J.D.
J.Med.Chem.
HeaderProtein Binding/Inhibitor
Released2012-09-28
Resolution1.620
CATH Insert Date04 Nov, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4hbxA01 11 Nov, 2012 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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