PDB 4h7c

PDB Information

PDB4H7C
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Synthesis and structure-activity relationships for 1-(4-(piperidin-1-ylsulfonyl)phenyl)pyrrolidin-2-ones as novel non-carboxylate inhibitors of the aldo-keto reductase enzyme AKR1C3.
Heinrich, D.M., Flanagan, J.U., Jamieson, S.M., Silva, S., Rigoreau, L.J., Trivier, E., Raynham, T., Turnbull, A.P., Denny, W.A.
Eur.J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-09-20
Resolution1.970
CATH Insert Date28 Mar, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4h7cA00 10 Apr, 2013 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3
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