PDB 4gpt

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Overview

PDB Information

PDB	4GPT
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells. Etchin, J., Sun, Q., Kentsis, A., Farmer, A., Zhang, Z.C., Sanda, T., Mansour, M.R., Barcelo, C., McCauley, D., Kauffman, M., Shacham, S., Christie, A.L., Kung, A.L., Rodig, S.J., Chook, Y.M., Look, A.T. Leukemia
Header	Protein Transport/Inhibitor
Released	2012-08-21
Resolution	2.220
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4gpt

4gpt

PDB 4gpt

Image of CATH 4gptA

4gptA

PDB Chain 4gptA

Image of CATH 4gptB

4gptB

PDB Chain 4gptB

Image of CATH 4gptC

4gptC

PDB Chain 4gptC

Image of CATH 4gptA00

4gptA00

CATH Domain 4gptA00

Image of CATH 4gptB00

4gptB00

CATH Domain 4gptB00

Image of CATH 4gptC00

4gptC00

CATH Domain 4gptC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped
B	05 Nov, 2012	Chopped
C	05 Nov, 2012	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4gptA00	25 Apr, 2013	3.40.50.300	Assigned
4gptB00	10 Nov, 2012	2.30.29.30	Assigned
4gptC00	28 Aug, 2013		Holding pen

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P62826	RAN_HUMAN	Homo sapiens	GTP-binding nuclear protein Ran
P41920	YRB1_YEAST	Saccharomyces cerevisiae S288C	Ran-specific GTPase-activating protein 1
P30822	XPO1_YEAST	Saccharomyces cerevisiae S288C	Exportin-1