PDB 4gm3
PDB Information
| PDB | 4GM3 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Homo sapiens |
| Primary Citation | High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction.
J.Am.Chem.Soc.
|
| Header | Transcription/Transcription Inhibitor |
| Released | 2012-08-15 |
| Resolution | 3.390 |
| CATH Insert Date | 18 Aug, 2013 |
PDB Images (25)
4gm3
PDB 4gm3
4gm3A
PDB Chain 4gm3A
4gm3B
PDB Chain 4gm3B
4gm3C
PDB Chain 4gm3C
4gm3D
PDB Chain 4gm3D
4gm3E
PDB Chain 4gm3E
4gm3F
PDB Chain 4gm3F
4gm3G
PDB Chain 4gm3G
4gm3H
PDB Chain 4gm3H
4gm3I
PDB Chain 4gm3I
4gm3J
PDB Chain 4gm3J
4gm3K
PDB Chain 4gm3K
4gm3L
PDB Chain 4gm3L
4gm3M
PDB Chain 4gm3M
4gm3N
PDB Chain 4gm3N
4gm3O
PDB Chain 4gm3O
4gm3P
PDB Chain 4gm3P
4gm3A00
CATH Domain 4gm3A00
4gm3B00
CATH Domain 4gm3B00
4gm3C00
CATH Domain 4gm3C00
4gm3D00
CATH Domain 4gm3D00
4gm3E00
CATH Domain 4gm3E00
4gm3F00
CATH Domain 4gm3F00
4gm3G00
CATH Domain 4gm3G00
4gm3H00
CATH Domain 4gm3H00
PDB Prints
PDB Chains (16)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 19 Aug, 2013 | Chopped |
| B | 19 Aug, 2013 | Chopped |
| C | 19 Aug, 2013 | Chopped |
| D | 19 Aug, 2013 | Chopped |
| E | 19 Aug, 2013 | Chopped |
| F | 19 Aug, 2013 | Chopped |
| G | 19 Aug, 2013 | Chopped |
| H | 19 Aug, 2013 | Chopped |
| I | 19 Aug, 2013 | Rejected |
| J | 19 Aug, 2013 | Rejected |
| K | 19 Aug, 2013 | Rejected |
| L | 19 Aug, 2013 | Rejected |
| M | 19 Aug, 2013 | Rejected |
| N | 19 Aug, 2013 | Rejected |
| O | 19 Aug, 2013 | Rejected |
| P | 19 Aug, 2013 | Rejected |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4gm3A00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3B00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3C00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3D00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3E00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3F00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3G00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
| 4gm3H00 | 27 Aug, 2013 | 2.130.10.10 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
| P61964 | WDR5_HUMAN | Homo sapiens | WD repeat-containing protein 5 |
