Lead Optimization of a 4-Aminopyridine Benzamide Scaffold To Identify Potent, Selective, and Orally Bioavailable TYK2 Inhibitors.
Liang, J., van Abbema, A., Balazs, M., Barrett, K., Berezhkovsky, L., Blair, W., Chang, C., Delarosa, D., Devoss, J., Driscoll, J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Halladay, J., Johnson, A., Kohli, P.B., Lai, Y., Liu, Y., Lyssikatos, J., Mantik, P., Menghrajani, K., Murray, J., Peng, I., Sambrone, A., Shia, S., Shin, Y., Smith, J., Sohn, S., Tsui, V., Ultsch, M., Wu, L.C., Xiao, Y., Yang, W., Young, J., Zhang, B., Zhu, B.Y., Magnuson, S.
J.Med.Chem.
