PDB 4gfm

PDB Information

PDB4GFM
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Lead identification of novel and selective TYK2 inhibitors.
Liang, J., Tsui, V., Van Abbema, A., Bao, L., Barrett, K., Beresini, M., Berezhkovskiy, L., Blair, W.S., Chang, C., Driscoll, J., Eigenbrot, C., Ghilardi, N., Gibbons, P., Halladay, J., Johnson, A., Kohli, P.B., Lai, Y., Liimatta, M., Mantik, P., Menghrajani, K., Murray, J., Sambrone, A., Xiao, Y., Shia, S., Shin, Y., Smith, J., Sohn, S., Stanley, M., Ultsch, M., Zhang, B., Wu, L.C., Magnuson, S.
Eur.J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-08-03
Resolution2.300
CATH Insert Date07 Jul, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gfmA01 09 Aug, 2013 3.30.200.20 Assigned
4gfmA02 09 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60674 JAK2_HUMAN Homo sapiens Tyrosine-protein kinase JAK2
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