PDB Information

PDB4GFG
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHomo sapiens
Primary Citation
A specific SYK inhibitor blocks B Cell Receptor, Fc Receptor, and Toll-like Receptor 9 pathways for the treatment of inflammatory diseases.
Hsu, J., Kim, Y., Hu, D.-Q., Xu, D., Zhang, J., Pashine, A., Menke, J., Whittard, T., Romero, N., Truitt, T., Lukacs, C., Zhou, M., Lucas, M., Slade, M., DeMartino, J., Tan, S.-L., Liao, C.
To be Published
HeaderTransferase/Transferase Inhibitor
Released2012-08-03
Resolution2.350
CATH Insert Date01 Sep, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 02 Sep, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4gfgA01 03 Sep, 2013 3.30.200.20 Assigned
4gfgA02 03 Sep, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
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