PDB Information

PDB4GE4
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-Based Design of Irreversible Human KAT II Inhibitors: Discovery of New Potency-Enhancing Interactions.
Tuttle, J.B., Anderson, M., Bechle, B.M., Campbell, B.M., Chang, C., Dounay, A.B., Evrard, E., Fonseca, K.R., Gan, X., Ghosh, S., Horner, W., James, L.C., Kim, J.Y., McAllister, L.A., Pandit, J., Parikh, V.D., Rago, B.J., Salafia, M.A., Strick, C.A., Zawadzke, L.E., Verhoest, P.R.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2012-08-01
Resolution2.410
CATH Insert Date11 Nov, 2012

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 Nov, 2012 Chopped
B 12 Nov, 2012 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4ge4A01 30 Aug, 2013 Holding pen
4ge4A02 30 Aug, 2013 3.40.640.10 Assigned
4ge4A03 30 Aug, 2013 3.90.1150.10 Assigned
4ge4B01 30 Aug, 2013 Holding pen
4ge4B02 30 Aug, 2013 3.40.640.10 Assigned
4ge4B03 30 Aug, 2013 3.90.1150.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8N5Z0 AADAT_HUMAN Homo sapiens Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Q8N5Z0 AADAT_HUMAN Homo sapiens Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
CATH-Gene3D is a Global Biodata Core Resource Learn more...