PDB Information

PDB4GB9
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta.
Murray, J.M., Sweeney, Z.K., Chan, B.K., Balazs, M., Bradley, E., Castanedo, G., Chabot, C., Chantry, D., Flagella, M., Goldstein, D.M., Kondru, R., Lesnick, J., Li, J., Lucas, M.C., Nonomiya, J., Pang, J., Price, S., Salphati, L., Safina, B., Savy, P.P., Seward, E.M., Ultsch, M., Sutherlin, D.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-07-26
Resolution2.440
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4gb9A01 10 Oct, 2013 3.10.20.90 Assigned
4gb9A02 10 Oct, 2013 2.60.40.150 Assigned
4gb9A03 10 Oct, 2013 1.25.40.70 Assigned
4gb9A04 10 Oct, 2013 3.30.1010.10 Assigned
4gb9A05 10 Oct, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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