PDB Information

PDB4G2W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and pharmacological evaluation of monocyclic pyrimidinones as novel inhibitors of PDE5.
Wang, G., Liu, Z., Chen, T.T., Wang, Z., Yang, H., Zheng, M., Ren, J., Tian, G., Yang, X., Li, L., Li, J., Suo, J., Zhang, R., Jiang, X., Terrett, N.K., Shen, J., Xu, Y.C., Jiang, H.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-07-13
Resolution2.280
CATH Insert Date04 Aug, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4g2wA00 13 Aug, 2013 1.10.1300.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O76074 PDE5A_HUMAN Homo sapiens cGMP-specific 3',5'-cyclic phosphodiesterase