PDB 4frj

PDB Information

PDB4FRJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer's Disease.
Huang, H., La, D.S., Cheng, A.C., Whittington, D.A., Patel, V.F., Chen, K., Dineen, T.A., Epstein, O., Graceffa, R., Hickman, D., Kiang, Y.H., Louie, S., Luo, Y., Wahl, R.C., Wen, P.H., Wood, S., Fremeau, R.T.
J.Med.Chem.
HeaderHydrolase/Inhibitor
Released2012-06-26
Resolution1.950
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4frjA01 10 Nov, 2012 2.40.70.10 Assigned
4frjA02 10 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
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