PDB 4fri
PDB Information
PDB | 4FRI |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Structure- and Property-Based Design of Aminooxazoline Xanthenes as Selective, Orally Efficacious, and CNS Penetrable BACE Inhibitors for the Treatment of Alzheimer's Disease.
J.Med.Chem.
|
Header | Hydrolase/Inhibitor |
Released | 2012-06-26 |
Resolution | 2.300 |
CATH Insert Date | 04 Nov, 2012 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 05 Nov, 2012 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4friA01 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
4friA02 | 10 Nov, 2012 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |