PDB Information

PDB4FJZ
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery and in Vivo Evaluation of Dual PI3K-beta/delta inhibitors
Gonzalez-Lopez de Turiso, F., Shin, Y., Brown, M., Cardozo, M., Chen, Y., Fong, D., Hao, X., He, X., Henne, K., Hu, Y.L., Johnson, M.G., Kohn, T., Lohman, J., McBride, H.J., McGee, L.R., Medina, J.C., Metz, D., Miner, K., Mohn, D., Pattaropong, V., Seganish, J., Simard, J.L., Wannberg, S., Whittington, D.A., Yu, G., Cushing, T.D.
J.Med.Chem.
HeaderTransferase/Inhibitor
Released2012-06-12
Resolution3.000
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4fjzA01 10 Oct, 2013 3.10.20.90 Assigned
4fjzA02 10 Oct, 2013 2.60.40.150 Assigned
4fjzA03 10 Oct, 2013 1.25.40.70 Assigned
4fjzA04 10 Oct, 2013 3.30.1010.10 Assigned
4fjzA05 10 Oct, 2013 1.10.1070.11 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P48736 PK3CG_HUMAN Homo sapiens Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
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