PDB Information

PDB4FGT
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
Tochowicz, A., Santucci, M., Saxena, P., Guaitoli, G., Trande, M., Finer-Moore, J., Stroud, R.M., Costi, M.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-06-04
Resolution2.000
CATH Insert Date28 Mar, 2013

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
D 28 Mar, 2013 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4fgtA00 02 Aug, 2013 3.30.572.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase