PDB 4fcr

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Overview

PDB Information

PDB	4FCR
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Davies, N.G., Browne, H., Davis, B., Drysdale, M.J., Foloppe, N., Geoffrey, S., Gibbons, B., Hart, T., Hubbard, R., Jensen, M.R., Mansell, H., Massey, A., Matassova, N., Moore, J.D., Murray, J., Pratt, R., Ray, S., Robertson, A., Roughley, S.D., Schoepfer, J., Scriven, K., Simmonite, H., Stokes, S., Surgenor, A., Webb, P., Wood, M., Wright, L., Brough, P. Bioorg.Med.Chem.
Header	Chaperone/Chaperone Inhibitor
Released	2012-05-25
Resolution	1.700
CATH Insert Date	04 Nov, 2012

PDB Images (3)

Image of CATH 4fcr

4fcr

PDB 4fcr

Image of CATH 4fcrA

4fcrA

PDB Chain 4fcrA

Image of CATH 4fcrA00

4fcrA00

CATH Domain 4fcrA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fcrA00	31 Aug, 2013	3.30.565.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P07900	HS90A_HUMAN	Homo sapiens	Heat shock protein HSP 90-alpha