Targeting conserved water molecules: Design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization.
Davies, N.G., Browne, H., Davis, B., Drysdale, M.J., Foloppe, N., Geoffrey, S., Gibbons, B., Hart, T., Hubbard, R., Jensen, M.R., Mansell, H., Massey, A., Matassova, N., Moore, J.D., Murray, J., Pratt, R., Ray, S., Robertson, A., Roughley, S.D., Schoepfer, J., Scriven, K., Simmonite, H., Stokes, S., Surgenor, A., Webb, P., Wood, M., Wright, L., Brough, P.
Bioorg.Med.Chem.
