PDB 4fa6

PDB Links
Overview

PDB Information

PDB	4FA6
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3Kalpha and mTOR Le, P.T., Cheng, H., Ninkovic, S., Plewe, M., Huang, X., Wang, H., Bagrodia, S., Sun, S., Knighton, D.R., LaFleur Rogers, C.M., Pannifer, A., Greasley, S., Dalvie, D., Zhang, E. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2012-05-21
Resolution	2.700
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4fa6

4fa6

PDB 4fa6

Image of CATH 4fa6A

4fa6A

PDB Chain 4fa6A

Image of CATH 4fa6A01

4fa6A01

CATH Domain 4fa6A01

Image of CATH 4fa6A02

4fa6A02

CATH Domain 4fa6A02

Image of CATH 4fa6A03

4fa6A03

CATH Domain 4fa6A03

Image of CATH 4fa6A04

4fa6A04

CATH Domain 4fa6A04

Image of CATH 4fa6A05

4fa6A05

CATH Domain 4fa6A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4fa6A01	10 Oct, 2013	3.10.20.90	Assigned
4fa6A02	10 Oct, 2013	2.60.40.150	Assigned
4fa6A03	10 Oct, 2013	1.25.40.70	Assigned
4fa6A04	10 Oct, 2013	3.30.1010.10	Assigned
4fa6A05	10 Oct, 2013	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform