PDB 4fa3

PDB Information

PDB4FA3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids; a New Class of Highly Potent and Selective Inhibitors of the Type 5 17-beta-hydroxysteroid Dehydrogenase AKR1C3
Jamieson, S.M., Brooke, D.G., Heinrich, D., Atwell, G.J., Silva, S., Hamilton, E.J., Turnbull, A.P., Rigoreau, L.J., Trivier, E., Soudy, C., Samlal, S.S., Owen, P.J., Schroeder, E., Raynham, T., Flanagan, J.U., Denny, W.A.
J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2012-05-21
Resolution2.200
CATH Insert Date04 Nov, 2012

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4fa3A00 10 Nov, 2012 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P42330 AK1C3_HUMAN Homo sapiens Aldo-keto reductase family 1 member C3
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