PDB Information

PDB4F95
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The human ITPA polymorphic variant P32T is destabilized by the unpacking of the hydrophobic core.
Simone, P.D., Struble, L.R., Kellezi, A., Brown, C.A., Grabow, C.E., Khutsishvili, I., Marky, L.A., Pavlov, Y.I., Borgstahl, G.E.
J.Struct.Biol.
HeaderHydrolase
Released2012-05-18
Resolution2.070
CATH Insert Date07 Jul, 2013

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4f95A00 09 Aug, 2013 3.90.950.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9BY32 ITPA_HUMAN Homo sapiens Inosine triphosphate pyrophosphatase