PDB 4f1s

PDB Links
Overview

PDB Information

PDB	4F1S
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold. Wurz, R.P., Liu, L., Yang, K., Nishimura, N., Bo, Y., Pettus, L.H., Caenepeel, S., Freeman, D.J., McCarter, J.D., Mullady, E.L., Miguel, T.S., Wang, L., Zhang, N., Andrews, K.L., Whittington, D.A., Jiang, J., Subramanian, R., Hughes, P.E., Norman, M.H. Bioorg.Med.Chem.Lett.
Header	Transferase/Inhibitor
Released	2012-05-07
Resolution	3.000
CATH Insert Date	04 Nov, 2012

PDB Images (7)

Image of CATH 4f1s

4f1s

PDB 4f1s

Image of CATH 4f1sA

4f1sA

PDB Chain 4f1sA

Image of CATH 4f1sA01

4f1sA01

CATH Domain 4f1sA01

Image of CATH 4f1sA02

4f1sA02

CATH Domain 4f1sA02

Image of CATH 4f1sA03

4f1sA03

CATH Domain 4f1sA03

Image of CATH 4f1sA04

4f1sA04

CATH Domain 4f1sA04

Image of CATH 4f1sA05

4f1sA05

CATH Domain 4f1sA05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Nov, 2012	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4f1sA01	10 Nov, 2012	3.10.20.90	Assigned
4f1sA02	10 Nov, 2012	2.60.40.150	Assigned
4f1sA03	10 Nov, 2012	1.25.40.70	Assigned
4f1sA04	10 Nov, 2012	3.30.1010.10	Assigned
4f1sA05	10 Nov, 2012	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform