PDB 4er5

PDB Information

PDB4ER5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Catalytic site remodelling of the DOT1L methyltransferase by selective inhibitors.
Yu, W., Chory, E.J., Wernimont, A.K., Tempel, W., Scopton, A., Federation, A., Marineau, J.J., Qi, J., Barsyte-Lovejoy, D., Yi, J., Marcellus, R., Iacob, R.E., Engen, J.R., Griffin, C., Aman, A., Wienholds, E., Li, F., Pineda, J., Estiu, G., Shatseva, T., Hajian, T., Al-Awar, R., Dick, J.E., Vedadi, M., Brown, P.J., Arrowsmith, C.H., Bradner, J.E., Schapira, M.
Nat Commun
HeaderTransferase/Transferase Inhibitor
Released2012-04-19
Resolution2.570
CATH Insert Date27 May, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4er5A01 01 Jul, 2013 1.10.260.60 Assigned
4er5A02 01 Jul, 2013 3.40.50.150 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q8TEK3 DOT1L_HUMAN Homo sapiens Histone-lysine N-methyltransferase, H3 lysine-79 specific
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