PDB 4ehg

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Overview

PDB Information

PDB	4EHG
Method	X-RAY DIFFRACTION
Host Organism	Trichoplusia ni
Gene Source	Homo sapiens
Primary Citation	Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties. Mathieu, S., Gradl, S.N., Ren, L., Wen, Z., Aliagas, I., Gunzner-Toste, J., Lee, W., Pulk, R., Zhao, G., Alicke, B., Boggs, J.W., Buckmelter, A.J., Choo, E.F., Dinkel, V., Gloor, S.L., Gould, S.E., Hansen, J.D., Hastings, G., Hatzivassiliou, G., Laird, E.R., Moreno, D., Ran, Y., Voegtli, W.C., Wenglowsky, S., Grina, J., Rudolph, J. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2012-04-02
Resolution	3.500
CATH Insert Date	07 Jul, 2013

PDB Images (7)

Image of CATH 4ehg

4ehg

PDB 4ehg

Image of CATH 4ehgA

4ehgA

PDB Chain 4ehgA

Image of CATH 4ehgB

4ehgB

PDB Chain 4ehgB

Image of CATH 4ehgA01

4ehgA01

CATH Domain 4ehgA01

Image of CATH 4ehgA02

4ehgA02

CATH Domain 4ehgA02

Image of CATH 4ehgB01

4ehgB01

CATH Domain 4ehgB01

Image of CATH 4ehgB02

4ehgB02

CATH Domain 4ehgB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	08 Jul, 2013	Chopped
B	08 Jul, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ehgA01	09 Aug, 2013	3.30.200.20	Assigned
4ehgA02	09 Aug, 2013	1.10.510.10	Assigned
4ehgB01	08 Aug, 2013	3.30.200.20	Assigned
4ehgB02	08 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf