PDB 4dtt

PDB Links
Overview

PDB Information

PDB	4DTT
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	Homo sapiens
Primary Citation	Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-beta hydrolysis. Charton, J., Gauriot, M., Guo, Q., Hennuyer, N., Marechal, X., Dumont, J., Hamdane, M., Pottiez, V., Landry, V., Sperandio, O., Flipo, M., Buee, L., Staels, B., Leroux, F., Tang, W.J., Deprez, B., Deprez-Poulain, R. Eur.J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2012-02-21
Resolution	3.220
CATH Insert Date	28 Mar, 2013

PDB Images (11)

Image of CATH 4dtt

4dtt

PDB 4dtt

Image of CATH 4dttA

4dttA

PDB Chain 4dttA

Image of CATH 4dttB

4dttB

PDB Chain 4dttB

Image of CATH 4dttA01

4dttA01

CATH Domain 4dttA01

Image of CATH 4dttA02

4dttA02

CATH Domain 4dttA02

Image of CATH 4dttA03

4dttA03

CATH Domain 4dttA03

Image of CATH 4dttA04

4dttA04

CATH Domain 4dttA04

Image of CATH 4dttB01

4dttB01

CATH Domain 4dttB01

Image of CATH 4dttB02

4dttB02

CATH Domain 4dttB02

Image of CATH 4dttB03

4dttB03

CATH Domain 4dttB03

Image of CATH 4dttB04

4dttB04

CATH Domain 4dttB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Mar, 2013	Chopped
B	28 Mar, 2013	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dttA01	31 Aug, 2013	3.30.830.10	Assigned
4dttA02	31 Aug, 2013	3.30.830.10	Assigned
4dttA03	31 Aug, 2013	3.30.830.10	Assigned
4dttA04	31 Aug, 2013	3.30.830.10	Assigned
4dttB01	31 Aug, 2013	3.30.830.10	Assigned
4dttB02	31 Aug, 2013	3.30.830.10	Assigned
4dttB03	31 Aug, 2013	3.30.830.10	Assigned
4dttB04	31 Aug, 2013	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme