PDB 4dpi

PDB Information

PDB4DPI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Highly potent macrocyclic BACE-1 inhibitors incorporating a hydroxyethylamine core: design, synthesis and X-ray crystal structures of enzyme inhibitor complexes.
Sandgren, V., Agback, T., Johansson, P.O., Lindberg, J., Kvarnstrom, I., Samuelsson, B., Belda, O., Dahlgren, A.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-02-13
Resolution1.900
CATH Insert Date04 Nov, 2012

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4dpiA01 10 Nov, 2012 2.40.70.10 Assigned
4dpiA02 10 Nov, 2012 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1