PDB 4dk5

PDB Links
Overview

PDB Information

PDB	4DK5
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Structure-based design of a novel series of potent, selective inhibitors of the class I phosphatidylinositol 3-kinases. Smith, A.L., D'Angelo, N.D., Bo, Y.Y., Booker, S.K., Cee, V.J., Herberich, B., Hong, F.T., Jackson, C.L., Lanman, B.A., Liu, L., Nishimura, N., Pettus, L.H., Reed, A.B., Tadesse, S., Tamayo, N.A., Wurz, R.P., Yang, K., Andrews, K.L., Whittington, D.A., McCarter, J.D., Miguel, T.S., Zalameda, L., Jiang, J., Subramanian, R., Mullady, E.L., Caenepeel, S., Freeman, D.J., Wang, L., Zhang, N., Wu, T., Hughes, P.E., Norman, M.H. J.Med.Chem.
Header	Transferase/Inhibitor
Released	2012-02-03
Resolution	2.950
CATH Insert Date	27 May, 2012

PDB Images (7)

Image of CATH 4dk5

4dk5

PDB 4dk5

Image of CATH 4dk5A

4dk5A

PDB Chain 4dk5A

Image of CATH 4dk5A01

4dk5A01

CATH Domain 4dk5A01

Image of CATH 4dk5A02

4dk5A02

CATH Domain 4dk5A02

Image of CATH 4dk5A03

4dk5A03

CATH Domain 4dk5A03

Image of CATH 4dk5A04

4dk5A04

CATH Domain 4dk5A04

Image of CATH 4dk5A05

4dk5A05

CATH Domain 4dk5A05

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	28 May, 2012	Chopped

CATH Domains (5)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4dk5A01	08 Jun, 2012	3.10.20.90	Assigned
4dk5A02	08 Jun, 2012	2.60.40.150	Assigned
4dk5A03	08 Jun, 2012	1.25.40.70	Assigned
4dk5A04	08 Jun, 2012	3.30.1010.10	Assigned
4dk5A05	08 Jun, 2012	1.10.1070.11	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P48736	PK3CG_HUMAN	Homo sapiens	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform