PDB Information

PDB4DHF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors.
Le Brazidec, J.Y., Pasis, A., Tam, B., Boykin, C., Wang, D., Marcotte, D.J., Claassen, G., Chong, J.H., Chao, J., Fan, J., Nguyen, K., Silvian, L., Ling, L., Zhang, L., Choi, M., Teng, M., Pathan, N., Zhao, S., Li, T., Taveras, A.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2012-01-27
Resolution2.800
CATH Insert Date04 Nov, 2012

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4dhfA01 10 Nov, 2012 3.30.200.20 Assigned
4dhfA02 10 Nov, 2012 1.10.510.10 Assigned
4dhfB01 10 Nov, 2012 3.30.200.20 Assigned
4dhfB02 10 Nov, 2012 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A